By who? Darren from Essex who drives a van, voted for Brexit, and thinks that immigrants would be OK if they came here to work rather than just stealing our jobs?
Soho is mostly pedestrianised as it is. Few people would drive there in the best of times, with the lack of parking, as the city is far too dense to accommodate that. Pedestrianising it (with common-sense exemptions for cabs, delivery vehicles and such where needed) would merely tidy up the status quo.