this post was submitted on 22 Nov 2023
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Who said anything about replacing clinical MCI exams with invasive scans? (I'm terrible; I didn't read the article. I wouldn't agree with replacing exams with invasive scans.) We just need better MCI exams. The ones we have now are flawed. They are not catching people who are clearly already symptomatic, and who therefore should be started on one of the existing options for small molecule drugs.
Also all of our current research uses the existing MCI exams for assessment and often endpoint, which deeply complicates things if the exams don't even catch what they were intended to catch.
These are the requirements to use the new anti amyloid drugs (the ones that purportedly do change disease progression, unlike current small molecule drugs), which need amyloid pet imaging plus regular mris to monitor for complications. Sorry if I was unclear.