I use both. For most of the time I use AdGuard, with the same block lists I use in Pi-Hole. The reason for this is I can set it up on devices and use it everywhere, not just at home. This is very easy on both iOS and Android. I also have my home router setup to use AdGuard. My electricity provider has more small outages than I would like which caused issues when things tried to come back online.
I use my Pi-Hole for my VPN which has a dedicated IP address. So when I'm out of the house working I can use the VPN and still take advantage of the Pi-Hole.
I've run a Pi-Hole for years, and AdGuard for the past year or so. Honestly, I've had zero issues with AdGuard and it requires zero maintenance. The Pi-Hole I still have to update and apply patches, to Pi-Hole and the OS. It's not a big deal, but AdGuard is set it and forget it.
Just my experience.