this post was submitted on 02 Feb 2024
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Science

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Study reveals why women are at greater risk of autoimmune disease (med.stanford.edu)
submitted 9 months ago by Gaywallet@beehaw.org to c/science@beehaw.org
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[โ€“] soaproot@sfba.social 4 points 9 months ago (1 children)

@Gaywallet This particular link wasn't opening for me. But what I have heard elsewhere is that there are indeed known to be a number of parts of the X chromosome which affect the immune system, in ways we are still in the process of figuring out.

[โ€“] jarfil@beehaw.org 2 points 9 months ago

It's an interesting article, and well exposed.

It basically goes to say that the inactivation mechanism (Xist noncoding RNA strand) which gets triggered when there are two X chromosomes present in a cell, almost completely coats one of the X chromosomes, disabling it... but the result is not completely inert, still allowing the attachment of other partial strands, in weird combinations that can lead to an (auto)immune response.