this post was submitted on 22 Mar 2025
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This thread made me look into the idea of DIYing it, and one of the search results I found looks like it legitimately is about actually doing the sequencing yourself:
https://techcrunch.com/2016/03/30/citizen-scientists-you-can-now-diy-your-own-dna-analysis/
$800 in 2016 was steep enough, but at the $1600 it apparently costs today I'm not sure it's still within the realm of DIY, if it ever really was. I wonder if there are any cheaper competitors?
That allows visualization of PCRed product, which is a far cry from whole genome sequencing. You can visualize a target at a time with no sequence info. Using it for sequences would be extremely tedious and require a lot of runs.
Yup, I used to do PCR genotyping. 50 samples running the same setup would take me a whole 12-hour day at my lower end lab.
I can't imagine having to do 50 different ones with 50 different templates and having to adjust each one. 😅 And that's for 50 sequences. How many are there in a human?
About 25,000 coding sequences and a lot more non-coding.