navigator.clipboard.read()/write() has been enabled (see documentation). A paste context menu will appear for the user to confirm when attempting to read clipboard content that is not originated from a same-origin page.
Very nice. The old execCommand API was annoying.
MV2 extensions should work in Thunderbird without modification. I've made a couple of simple extensions that work like a charm in both Firefox and Thunderbird, but I'm not sure if more complex extensions would have issues. The documentation says thus:
Some MV3 extensions will not work in Thunderbird. See this page for list of missing functionality.