As someone who occasionally read Dilbert back in the day, I do have to say that the "author self-insert character is always right and always complaining, and everyone else is always an idiot" tropes are well-tilled soil for right-wing outrage culture.
Add in there that he already had an "perpetually angry woman" character and "Indian office worker stereotype" character, and it becomes even easier to see how he got there.
He's even dumber than that. He's not just saying "could be the vaccine, could be not"; he's literally saying "you can't say it's the vaccine and you can't say it's not."
He's managed to say less than nothing.
As a frustrated Christian, I think I'd say it's most accurate to say that Trump embodies Conservatives, Republicans, and Evangelicals, all of whom have apparently no clear code of conduct or definition beyond "seize power, worship the perceived strong man, crush the marginalized."
Christian, though...there's a least a definition there ("follower of Christ") that excludes Trump — not only does Trump not care at all about Christ except as an incantation to get votes, but he directly contradicts the things Christ taught.
It seems mostly like a boomer thing to do, honestly; I don't really hear "I hate my wife/husband" jokes from folks my generation (Millennials) or younger. Honestly, I mostly hear "I hate myself" jokes there.
A lot of the "ol' ball and chain" etc jokes tend to be more frequently casting the wife as the enemy instead of the husband, too, so there's some definite boomer misogyny as key element.