TechTakes

it does seem mildly useful https://www.science.org/content/blog-post/screening-against-alphafold-models-maybe-better-it-looks

note that google's thing is pattern matching, and if there's few similar protein structures in literature, then alphafold is working on poor quality data. comments do notice a red flag or two

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lol. the sheer fucking hubris.

Their comments section just never fails to deliver ... something.

Online communities with reasonable debate are under attack by state actors, HN is no exception. In this context, no matter how well meaning the proposal is, opening an avenue for acrimony here is not something we can afford.

At least this dead hedge fund guy has a wikipedia "controversies" section as a legacy. I wonder if a genius mathematician could figure out a way to enrich his friends and family while the markets took a dump.

According to The Wall Street Journal in May 2009, Simons was questioned by investors on the dramatic performance gap of Renaissance Technologies' portfolios. The Medallion Fund, which has been available exclusively to current and past employees and their families, surged 80% in 2008 in spite of hefty fees; the Renaissance Institutional Equities Fund (RIEF), owned by outsiders, lost money in both 2008 and 2009; RIEF declined 16% in 2008.