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I know this is an odd answer, and may not be for everyone. I got the prescription filled, and held the dose in my hand and asked it: "will you hurt me?" And worked with that in meditation. It said it was okay to take. These days, I'm more inclined to research the heck out of it online before starting any drug, any reason. (And: I would never do this with a rando drug which came from who-knows-where.)
If you don't like how you feel, after giving it a fair shake (several weeks, whether you want to see the change as blood plasma concentrations or rearrangement of neural pathways), you can stop. You're not committing to it forever and ever; the effects will wear off once you stop taking it.
If you do want to stop, be sure to contact the prescribing doctor—or if the doc is unavailable, at the very least a pharmacist. Some drugs for depression need a gradual tapering-off schedule to avoid nasty effects of going cold turkey.
Good tip, thanks! I did read somewhere that scheduling dose increases and decreases is extremely important with this class of medication, so I'll definitely only do it with a doctor who can observe me closely.