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Researchers discover localized pain relief using known chemical reaction (phys.org)

submitted 1 week ago by Daryl76679@lemmy.ml to c/biology@mander.xyz

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[–] Catoblepas@lemmy.blahaj.zone 7 points 1 week ago (1 children)

Gabapentin is cool and everything, but if this new stuff doesn’t have any bad side effects I’d love to try it. Gabapentin gives me slow brain at effective doses, and it seems like something that only activates at the pain site could potentially avoid systemic effects like that.

[–] tenchiken@lemmy.dbzer0.com 5 points 1 week ago (1 children)

If gabapentin is effective but side effects are an issue, you might see benefit from pregabalin (Lyrica). I had similar issues with gabapentin brain fog at the doses I needed for a cervical spine injury.

The description my pharmacist gave when I talked to her was basically all the good stuff turned way up, side effects turned way down.

I'm on high dose of pregabalin now and it's been life altering.

I'm watching this potentially also, but in the meantime I'm at least functional.

[–] Catoblepas@lemmy.blahaj.zone 3 points 1 week ago

Thanks for the info! I’ll bring it up with my doctor.