this post was submitted on 15 Nov 2023
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I've been on a million medications for a million things, I get some fairly bad side effects sometimes but it's almost always physical, and I've never had side effects from a painkiller before this, and I don't know how unusual this is, but on tramadol I had the wildest mood swings of my life. I was on holiday when taking it, and I don't know if I took too much or another medication fucked with it, but one minute I was doing what my mate called a "frog dance" in the pool in complete bliss laughing my head off, then I was angrier than I've ever been, then I was incredibly depressed in a very short space of time where literally nothing happened to cause any of it. I'd never experienced anything like it, it was horrible and I never want to take it again.
Tramadol also acts as an SNRI (similar to antidepressants cymbalta and Effexor) in addition to acting on opioid receptors. Might be why it felt odd.